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NanoBio Protect

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Frequently Asked Questions About NanoBio Protect

About NanoBio Protect

What is NanoBio® Protect?

NanoBio Protect offers next-level protection to help keep you and your family healthy. It is the only alcohol-free nasal antiseptic proven to kill 99.99% of infection-causing germs when applied to the skin in and around the nose. Easy to apply with any cotton swab, the oil-based nano-formulation also moisturizes the skin and is fragrance-free.  

NanoBio Protect uses patented, natural-oil nanodroplets that deliver the antiseptic directly to the surface of germs, killing them on contact. Uniquely, the nanodroplets remain active on the skin after application for up to 8 hours (in lab testing), providing lasting protection against the germs that cause infection.

Who developed NanoBio Protect?

NanoBio Protect was developed by BlueWillow Biologics, Inc., a biopharmaceutical company headquartered in Ann Arbor, MI with a twenty-year history of researching and developing vaccines and topical antiseptics. The nanodroplet technology used in the company’s products was supported by grants from the NIH, the US Department of Defense, and the Gates Foundation among others.

Why is it important to use NanoBio Protect?

Hand sanitizers only last on hands for a few minutes, so they must be reapplied every time you touch a potentially contaminated surface. NanoBio Protect provides next-level protection against infection-causing germs. Along with frequent hand-washing, wearing face coverings, and social distancing, NanoBio Protect is an essential part of a daily regimen that helps keep families healthy.

Infections can occur when we touch a contaminated surface and then transfer the germs to our face – particularly to our nose. Protecting the skin in and around the nose is crucial, as the nose is the key entry point for most respiratory infections. 


The average person touches his or her face and nose 23 times per hour. [Source: Kwok et al. Am J Infect Control. 2015 Feb;43(2):112-4. doi: 10.1016/j.ajic.2014.10.015. Face Touching: A Frequent Habit That Has Implications for Hand Hygiene.


NanoBio Protect labeling advises it "helps reduce bacteria on the skin that could cause infection." Is it indicated to kill specific bacteria? Is there related research?

Yes. In lab tests, NanoBio Protect has demonstrated the ability to kill 99.99% of infection-causing germs tested, including a broad spectrum of bacteria. Details on the pathogens against which NanoBio Protect is effective in lab testing is available for medical professionals at

How is nanotechnology used in NanoBio Protect?

NanoBio Protect works because of its patented nano-formulation. The product’s unique, oil-based nanodroplets enhance the antiseptic’s antimicrobial activity, optimizing its ability to kill germs on the skin. The nanodroplets are small enough to be effective on the skin, but too large to be absorbed into the bloodstream — creating a layer of lasting protection.  

NanoBio Protect adds BZK antiseptic to the surface of nanodroplets. This technology offers four distinct advantages over conventional BZK antiseptics:

  • The Nanodroplets optimize the ability of the antiseptic to kill germs.
  • The droplets sit on skin after application, enabling protection for up to 8 hours (in lab testing).
  • Dry skin allows germs to penetrate. Nanodroplets hydrate the skin, preventing dryness and cracking.
  • When bound to the oil-based Nanodroplets, the antiseptic does not irritate the skin.

Can you provide more detail on how the nano-technology works?

NanoBio Protect is composed of positively-charged droplets that are 300-600nm in size. These droplets are attracted to negatively-charged germs on the skin. The nanodroplets deliver the antiseptic BZK to the surface of the germs where the germ is inactivated via membrane disruption.

Other conventional BZK antiseptics often combine BZK with water, causing crystallization. When crystallization occurs, it rapidly inactivates the antiseptic and can lead to skin irritation. But because each NanoBio Protect droplet carries a positive charge, the droplets repel each other — keeping the BZK molecules separated and preventing crystallization.  

Is nano-technology as used in this product safe?

Yes. NanoBio Protect and similar NanoBio formulations have been tested extensively in animal and human studies involving topical application. These studies demonstrate conclusively that topical NanoBio products are not absorbed systemically and are non-irritating. The products are alcohol-free and cannot be absorbed through the skin and into the bloodstream.

How does NanoBio Protect work?

NanoBio Protect uses patented nanodroplets in conjunction with an active antiseptic (0.13% BZK). NanoBio Protect droplets are scientifically designed to target and kill germs. The nanodroplets enhance the antiseptic’s antimicrobial activity, optimizing its ability to kill germs on the skin. 

What is the active ingredient in NanoBio Protect?

NanoBio Protect contains 0.13% benzalkonium chloride (BZK), a safe and effective  OTC antiseptic in use for decades.* What is unique about NanoBio Protect is that the BZK is attached to patented, natural-oil nanodroplets. These nanodroplets allow the BZK to persist and remain active on the skin for hours after the antiseptic is applied. Unlike alcohol-based and other BZK antiseptics that irritate the skin, oil-based nanodroplets moisturize the skin. 

*BZK was first used in 1950

Is NanoBio Protect an antibiotic or vaccine?

No. NanoBio Protect is not a vaccine or an antibiotic. NanoBio Protect is not a vaccine or an antibiotic. NanoBio Protect is a new, highly effective skin antiseptic. It is the only alcohol-free, moisturizing nasal antiseptic proven to kill 99.99% of infection-causing germs on contact. It is easy to apply with any cotton swab and pleasant to use on skin in and around the nose — the key entry point for respiratory infections.


Can children use NanoBio Protect?

Yes. NanoBio Protect is safe to use for children under 12 years of age. As with any medication, always apply under adult supervision. For children under 2 years of age, ask your doctor before using.

This product is meant for external use only. Keep the product out of reach of children and heed all product directions and warnings prior to use.

Is NanoBio Protect safe?

Yes. Along with frequent hand washing and minimal face touching, applying NanoBio Protect can protect you and your family from infection-causing germs.

NanoBio Protect is well tolerated and non-irritating, and its patented formulation gently moisturizes nasal skin. 

Is NanoBio Protect US FDA regulated?

Yes. NanoBio® Protect nasal antiseptic adheres to the OTC monograph system for topical skin antiseptics. In testing by independent FDA registered laboratories, NanoBio® Protect was shown to kill 99.99% of a broad spectrum of pathogens.

Is NanoBio Protect comfortable to use?

NanoBio Protect is soothing and easy to use!

What testing has been done to demonstrate safety?

Extensive studies on the family of NanoBio formulations, including NanoBio Protect, demonstrate that NanoBio products applied to the skin are non-irritating, non-toxic and are not absorbed through the skin and into the bloodstream. Further details for medical professionals are available at NanoBio Protect has over 1000 ratings & reviews on Amazon that are overwhelmingly positive.

If I use NanoBio Protect, do I still need to wash my hands?

Yes. Along with frequent handwashing, wearing face coverings, and social distancing, applying NanoBio Protect every day will help safeguard you and your family from infection-causing germs.

Can pregnant women use NanoBio Protect?

As with any drug, if you are pregnant, ask your doctor before using.

Is NanoBio Protect gluten- and dairy-free?


If I am allergic to soy, can I use this product?

While NanoBio Protect uses highly purified soybean oil, you should still check with your doctor before use. 

Does NanoBio Protect kill both the “good” and “bad” bacteria in the nose?

NanoBio Protect works with your body's natural defenses against infection. The beneficial bacteria that inhabit the mucosa of the nose are not affected by NanoBio Protect, because when used as directed, NanoBio Protect only kills germs on the skin in & around the nose, as well as bad germs that arrive for up to 8 hours after application

How to Use NanoBio Protect

How do I apply NanoBio Protect?

NanoBio Protect can be used with any cotton swab. When applying the product, use a new swab for each nostril. Thoroughly swab the skin around the rim of the nose as well as the skin up to one-half inch inside each nostril to kill germs that can cause infections. 

How long does NanoBio Protect work?

NanoBio Protect kills germs on contact, and persists on the skin to continue killing germs for 8 hours after application

How often can the product be applied?

NanoBio Protect can be used every 4 hours as needed.

How many doses of NanoBio Protect are in a bottle?

Each bottle of NanoBio Protect includes 18ml of solution providing at least 40 treatments. Each treatment includes application to both nostrils.

Manufacturing Information

Who is the manufacturer/marketer and where is the company based?

BlueWillow Biologics, Inc., Ann Arbor, MI

Where is the product manufactured?

The product is manufactured at an FDA GMP manufacturing facility in the U.S.A.

When did the product launch?

NanoBio Protect launched on April 2, 2020.

Where to Buy NanoBio Protect

Where can I buy commercial quantities of NanoBio Protect?

NanoBio Protect is also partnering with professional channel distributors including:

  • US Compliance
  • DQE Ready
  • Market Lab
  • Scrip
  • Smartfill
Where can I buy NanoBio Protect?

NanoBio Protect is available online at:

In stores:


How long does it take to receive my order?

For standard shipping, orders typically leave the facility within 5 to 7 days. 

We also offer two-day express shipping. 

What is your shipping policy?

Your order may be shipped via FedEx, USPS, UPS, or other couriers. Couriers vary depending on location. Check your confirmation email for exact shipping details. 

Shipping cost: Standard shipping is free on all orders. For expedited shipping, we will charge a $5 shipping fee per order. 

Delivery times: Standard shipping orders process within 5 to 7 business days. Expect two-day express shipping to arrive within 48 hours. 

Confirmation and Tracking: You will receive an email confirming your order. When your order ships, you will receive a tracking number from your courier.  

For questions related to shipping, contact the courier directly.

What’s your return policy?

We offer reimbursements for products that are damaged before or during the shipping process. We also process refunds for unopened boxes of product sent back in their original condition. Once the returns process is initiated, you will have 30 days to return the product.

We will not refund used or opened boxes of product, or products where the original packaging has been damaged after delivery.  

To initiate the return process, contact us directly at: 

Does my order include cotton swabs or an applicator?

No, cotton swabs must be purchased separately. 

I’m a pharmacy or retailer interested in carrying NanoBio Protect.

Please email our sales team at: 

Where does NanoBio Protect ship from?

Our products ship from various warehouses across the US. Your order will be shipped from the warehouse closest to the destination zip code to ensure fast processing. 

Does NanoBio Protect ship outside the US?

We currently ship only to the continental US and Hawaii.  

Can’t find what you’re looking for?

Contact us directly. Email us at: